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Lena Meyer, Anna Maria Elert, Claudia Koch
A digital Quality Infrastructure for testing and calibration laboratories: from theory to practice

The digital Quality Infrastructure (QI) offers significant potential to enhance the technical excellence and efficiency of laboratory operations. By leveraging tools and processes of a digital QI, laboratories, their customers, authorities, and other stakeholders can enhance efficiency, foster trust, and generate added value. This paper introduces the digital QI toolset and ecosystem as developed in the German initiative QI-Digital, and explores concrete scenarios for their implementation in laboratories. Successful rollout not only requires technical development but also intense stakeholder engagement. Consequently, this paper shares insights and outcomes from a structured stakeholder dialogue with the laboratory community, and outlines the establishment of the 'digital LabHub' as a pivotal step to drive digital transformation and facilitate the widespread adoption of digital QI within laboratories and their broader ecosystem.

Sergio Oliveira
Some Aspects of Metrological Traceability as a Consequence of Blending Low-carbon Hydrogen to Natural Gas Pipelines in Brazil

This work analyzes the readiness of low-carbon hydrogen to be blended to natural gas, or eventually a mixture of natural gas and biomethane, transmission pipelines network in Brazil with metrological traceability. An approach involving Quality Infrastructure, metrological reliability, and the description of both the main parts of natural gas networks and the hydrogen embrittlement phenomenon was used to obtain an overview of their joint effects in pipelines´ parts. On analyzing all aspects described before with the most relevant international standards applicable in pipelines, there was a lack of information on Metrology quantities flow rate, pressure, density, composition, calorific value and measuring stations, so it was possible to conclude what is necessary in Brazil in terms of existing pipelines that transport natural gas to blend with hydrogen.

Qinmi Sun, Haibin Li
Research on Intelligent Traceability Framework for Trusted Artificial Intelligence

With the deep integration of artificial intelligence and big data technology, the self-learning ability of the system brings efficiency improvement, but problems such as data pollution, algorithm black box, and model drift exacerbate the difficulty of tracing. This article proposes a three-layer traceability framework (TVB-Trace) that integrates blockchain metadata anchoring, dynamic verification mechanism, and trusted execution environment. By constructing a verifiable data lineage graph and algorithm decision chain throughout the entire lifecycle, it achieves transparent supervision of AI self-learning systems. Experiments have shown that this framework can improve data traceability accuracy to 99.2% and enhance model decision interpretability by over 40%. (Keywords: artificial intelligence traceability, blockchain, trusted computing, self-learning system).

Paola Iacomussi
3D printed Reference Materials for optical properties

INRIM developed and patented digitally designed Reference Materials (RM) for luminance coefficient quantity, manufactured by 3D printing. This method offers IoT (Internet of Things) solutions for producing RM representative of perceived properties as the spatial distribution of the luminance (luminance coefficient), a quantity crucial for lighting design, especially in road lighting. Dedicated RMs for luminance coefficient enhance metrological capabilities, and lead to safer and better-illuminated roads.

Boymatov Normurod, Khayrullaev Makhmud, Khakimov Ortogali
Minimizing the risks of making decisions on conformity assessment in the production of CRM for construction laboratories

The risks of making decisions on conformity assessment are analyzed using the example of rebar from a large Uzbek manufacturer and a small business. An interlaboratory comparison was organized using the capabilities of an accredited proficiency testing provider for the following indicators: cross-sectional area, yield strength and tensile strength of rebar (GOST 12004). The indicators are measured by a fixed value of steel density - 7850 kg/m³. An analysis of the risks of using the measured and fixed value of rebar density for these indicators is carried out. An improvement of the measurement method, an analysis of the contributions to measurement uncertainty and the value of scatter are proposed. Further prospects for the development of certified reference material for the above indicators are also proposed.

Abraham de Guzman, Elyson Keith Encarnacion
Performance Comparison of a Self-Cleaning and a Conventional pH Electrode in Wastewater Process Monitoring

Accurate pH measurement is vital in wastewater treatment for effective process control and regulatory compliance. This study compares a self-cleaning pH sensor (HORIBA 6122 series) with a conventional glass electrode, installed in parallel at a wastewater treatment facility in Metro Manila, Philippines. Over a 97-day period, 2,324 paired readings were recorded. Statistical analysis revealed a significant difference (t(2323) = 56.88, p > 0.05) in mean values (HORIBA = 6.93, conventional = 6.12). The HORIBA sensor exhibited lower variability (HORIBA = 0.2335, conventional = 0.6461) through time, indicating better stability. These results align with the goals of Process Analytical Technology and support the deployment of self-cleaning sensors for real-time wastewater treatment monitoring.

Kateryna D’Ayala, Dmytro Nykonenko, Anzhelika Kolesnychenko, Oleh Yatsuk, Patrizia Davit, Monica Gulmini
Quantitative Analysis of Glass Artifacts from Mykolayiv and Zaporizhzhia Oblasts (southern Ukraine): a Multi-Scale Approach

This study explores approaches to investigate archaeological glass artifacts and discuss the merits of a multi-scale approach integrating macroscopic characteristics with microanalysis to shed light into the routes of glass exchange in the past populations and on glass production techniques. Two case studies from southern Ukraine are considered: Hellenistic core-formed vessels from Olbia Pontica (5th c. BCE – 1st centuries CE) and Scythian beads from Khortytsia (5th-4th centuries BCE). SEM-EDS analysis of the Olbia glass led a preliminary classification into Types II and III, linked to Syro-Palestinian and Egyptian productions. The Khortytsia beads underwent in-depth analysis using LA-ICP-MS, XRD, and FORS, allowing a more detailed classification based on trace elements, as well as identification of opacifiers and colorants. The beads were divided into two groups according to TiO₂ and CaO concentrations, aligning with Iron Age production centres of glass in Egypt and the Levant.

Kim Christopher C. Aganda, Zamantha Nadir Z. Martin, Annabelle V. Briones, Rachel Zioness O. Diputado, Encar Alej D. Mendoza, Jaryl T. Jihad, Hernando P. Bacosa
Multivariate Analysis on Samples from the 2024 Manila Bay Oil Spill

The 2024 Manila Bay oil spill was an impact of the monsoon rains enhanced by Super Typhoon Carina. Investigations utilizing chemical forensics were conducted to evaluate the impact of the accident. In this study, the application of multivariate analysis to aid the assessment was also explored. Samples collected at different points around the spill site and nearby coastal areas were prepared by extraction with dichloromethane followed by drying over sodium sulfate, while analysis was accomplished using gas chromatography – mass spectrometry (GCMS) in Scan and SIM modes. Common diagnostic biomarkers were used for comparison of the different oil samples. Principal component analysis and K-means clustering were also performed. The study aims to provide an alternate approach to gaining insights into the properties of oil samples. The study also emphasizes the vital role of chemical measurements in making informed decisions and response efforts during environmental crises.

Elyson Keith P. Encarnacion, Winnie P. Alejandro, Rizel Marie S.M. Ting, Anne C. Alcantara, Agaseve F. Del Rosario, Ellaine R. Dioso, David J. Alcarde Jr.
Preliminary Assessment of Total UV-Absorbing Contaminants Migrating from Philippine-based Microwavable Containers to Fatty / Oily Food Simulant using Modified 21 CFR Part 177 Method

Single-use microwavable containers are commonly employed to package food products because they are perceived as convenient, durable, and safe. In this study, a modification of 21 CFR Part 177 validated by Alejandro et al. to profile low-density polyethylene (LDPE) bags was used to assess rigid microwavable polypropylene (PP) food packaging. A Welch two-sample t-test between LDPE and PP samples (n=15) yielded tstat = 0, and p (1.00) > 0.05, confirming method robustness. Spectral scanning of 21 brands of Philippine-based microwavable PP containers resulted in a range of 0.008-0.199 AU, indicating large variability. Of the samples analyzed, 23.8% were above the 0.1 AU maximum allowable limit set by the FDA Philippines, implying possible chemical migration upon contact with high-fat, low-moisture food products typically sold in local eateries and quick-service restaurants. Further investigations include migration studies at non-ambient conditions and to other food simulants, and targeted and quantitative analyses.

Anne C. Alcantara, Elyson Keith P. Encarnacion, Rizel Marie S.M. Ting, Winnie P. Alejandro, Harold E. Armario, Agaseve F. Del Rosario, David J. Alcarde Jr.
Method Validation and Chemometric Analysis of UV-Absorbing Contaminant Migration from Low-density Polyethylene Packaging Materials into 8% Ethanol

Ensuring food packaging safety is vital due to potential chemical migration. This study validated an extraction method using 8% ethanol, a simulant for alcoholic products per US 21 CFR Part 177, and evaluated the influence of LDPE thickness on total UV-absorbing contaminants (TACs). Twenty-two samples (6–130 μm thick) from 13 Mega Manila locations were tested. Method validation showed limits of detection (LOD) and quantification (LOQ) of 0.010 and 0.025 Au, respectively. Repeatability and intermediate precision were acceptable, with %RSDs from 8.5% to 35.8%. All absorbance values were below the Philippine FDA limit (0.300 Au), with PE-0008 and PE-0022 having the highest (0.154 and 0.123 Au). Chemometric analysis showed a moderate positive correlation between thickness and TACs (Spearman’s ρ = 0.481), though Kruskal-Wallis (p = 0.2042) and LOESS regression indicated thickness alone doesn't drive migration. K-means clustering and LOESS trends suggest peak migration at 30–40 μm. Future work should apply chromatographic techniques for comprehensive LDPE safety assessment.

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