Practical solutions to the biodeterioration dilemma: activity of Dittrichia viscosa extracts and its specialized metabolites on standard organism Raphidocelis subcapitata |
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| Alessandro De Rosa, Marco Morelli, Marco Masi, Alessio Cimmino, Andrea Carpentieri, Gaia Marzia Silvestre, Antonino Pollio, Paola Cennamo |
- Abstract:
- Biodeterioration caused by microorganisms is among the most pressing challenges in the conservation of outdoor stone heritage. In the search for sustainable solutions, the application of plant-extracted bioactive compounds has been gaining increasing attention. This study investigates the biocidal potential of extracts from Dittrichia viscosa, a ruderal Mediterranean plant rich in antibiotic and allelopathic compounds. Crude extracts were obtained using solvents of increasing polarity and characterized via NMR and GC-MS to identify major bioactive constituents. Four sesquiterpenoids—α-costic acid and inuloxins A, B and C—were identified as the most promising in terms of biocidal activity and contextually isolated and tested on pure cultures of the green alga Raphidocelis subcapitata. Inuloxin A and C significantly reduced algal growth in a dose-responsive manner, while α-costic acid and inuloxin B showed no inhibitory effect. These findings confirm the biocidal effectiveness of these specialized metabolites and support their potential future application in the treatment of biological patinas.
- Download:
- IMEKO-Metroarchaeo-2025-022.pdf
- DOI:
- 10.21014/tc26-2025.022
- Event details
- IMEKO TC:
- TC26
- Event name:
- TC26 MetroArcheo Conference 2025
- Title:
Metrology for Archaeology and Cultural Heritage
- Place:
- Bergamo, ITALY
- Time:
- 15 October 2025 - 17 October 2025